Can the Prognosis be Predicted in Subacute Thyroiditis?

Authors : Ali SAKLAMAZ, Özcan ÇİFTÇİ

Pages : 14-20

Doi:10.29058/mjwbs.1221562

View : 21 | Download : 12

Publication Date : 2023-04-28

Article Type : Research Paper

Abstract :Aim: Subacute thyroiditis insert ignore into journalissuearticles values(SAT); is a thyroid disease that seriously affects the quality of life for patients caused by acute inflammation of the thyroid gland. Apart from classical acute phase reactants, the values and rates obtained from peripheral blood count insert ignore into journalissuearticles values(mean platelet volume insert ignore into journalissuearticles values(MPV);, neutrophil-to-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, and platelet-to-lymphocyte ratio insert ignore into journalissuearticles values(PLR);); values are also accepted as practical indicators of systemic inflammation. Our aim in this study is to compare the effects of systemic inflammation markers and the treatments given in the laboratory tests of our patients with a diagnosis of SAT, on the hypothyroid state one year later. Material and Methods: In this study, which was carried out with a retrospective method, 133 patients were included in the study. The medical data of these patients at the time of SAT diagnosis and one year later were analyzed. 37 patients were in the steroid group and 97 patients were in the nonsteroidal anti-inflammatory drug insert ignore into journalissuearticles values(NSAID); group. Results: The male/female ratio was similar in both groups. Female dominance was observed in both groups in patients diagnosed with SAT. The thyroid tests of the groups, which were hyperthyroid at the beginning and euthyroid one year later, were similar between the groups insert ignore into journalissuearticles values(p>0.05);. Both groups had an increase in acute phase reactants at baseline insert ignore into journalissuearticles values(erythrocyte sedimentation rate [ESR] and C-reactive protein insert ignore into journalissuearticles values(CRP); levels); and normalized after treatment. Neutrophil insert ignore into journalissuearticles values(p 0.05); and platelet insert ignore into journalissuearticles values(p 0.05);. Conclusion: Inflammation markers and treatments applied in SAT patients did not have a significant effect on the prognosis
Keywords : Subakut tiroidit, glukokortikoid, NSAİİ, hipotiroidizm