Mean Platelet Volume as a New Inflammatory Marker in Acute Pancreatitis and Its Relation to C-Reactive Protein and Ranson’s Score on Admission

Authors : Baris KARAGÜN, Tayyibe SALER

Pages : 9-13

Doi:10.29058/mjwbs.1228491

View : 105 | Download : 25

Publication Date : 2023-04-28

Article Type : Research Paper

Abstract :Aim: The study’s aim is to evaluate mean platelet volume insert ignore into journalissuearticles values(MPV); as a marker of inflammation in patients with acute pancreatitis insert ignore into journalissuearticles values(AP); and to analyse the relationships among MPV, CRP insert ignore into journalissuearticles values(C-reactive protein); and Ranson’s score. Material and Methods: In this study, 119 patients with AP insert ignore into journalissuearticles values(mean age 53.8 ± 18.0 years); and 88 healthy control group insert ignore into journalissuearticles values(mean age 53.1 ± 6.8 years); were enrolled. Among the patients with AP, 75 were classified as having biliary AP, and 44 were classified as having nonbiliary AP. All patients’ demographic data, clinical and laboratory findings and Ranson’s scores were examined from the hospital’s database. Results: MPV was significantly lower among patients with AP than among the control group insert ignore into journalissuearticles values(p = 0.001);. CRP was significantly higher among patients with AP than among the control group insert ignore into journalissuearticles values(p< 0.001);. The difference in MPV between the biliary and nonbiliary AP group was statistically not significant. When we compared MPV based on patients’ lengths of hospital stay, there was no significant difference. In correlation analysis, there was no correlation among CRP, Ranson’s score and serum MPV levels. Conclusion: We observed that MPV levels in the AP group were lower than healthy controls. Thus, like other inflammation markers, MPV might be a useful marker for AP diagnosis.
Keywords : Akut pankreatit, Ortalama trombosit hacmi, inflamasyon

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