Effects of Anemia on Clinical Outcomes in Hospitalized Patients with COVID-19 Pneumonia

Authors : Hilal KURTOĞLU GÜMÜŞEL, Selçuk GÖRMEZ, Ömer ÖZÇAĞLAYAN, Burak PAMUKÇU

Pages : 316-322

Doi:10.31067/acusaglik.1039533

View : 42 | Download : 19

Publication Date : 2022-07-01

Article Type : Research Paper

Abstract :Objective: We aimed to examine the role of anemia on clinical outcomes including intensive care unit insert ignore into journalissuearticles values(ICU); admission and mechanical ventilation insert ignore into journalissuearticles values(MV); in coronavirus disease 2019 insert ignore into journalissuearticles values(COVID-19); patients. Materials and methods: Totally 175 hospitalized COVID-19 patients were retrospectively included. Patients with a hemoglobin level of <12 g/dL in women and <13 g/dL in men constituted the anemic group, while COVID-19 patients with normal hemoglobin levels constituted the non-anemic group. A logistic regression analysis was performed to investigate the role of anemia and serum ferritin value for prediction of ICU and MV requirement. Results: Of patients, 46 insert ignore into journalissuearticles values(45.7%, 21 men); had anemia and 129 insert ignore into journalissuearticles values(68.2%, 88 men); had normal hemoglobin levels. The ICU requirement and MV rates were significantly higher in anemic group compared to non-anemic group insert ignore into journalissuearticles values(30.4% vs. 15.5%, respectively; p=0.028 and 23.9% vs. 10.9%, respectively; p=0.030);. Median length of hospital and ICU stay was longer in patients with anemia insert ignore into journalissuearticles values(10.5 days vs. 8 days, respectively; p=0.047 and 0 days vs. 0 days, respectively; p=0.027);. Anemia and ferritin were significant risk factors for ICU admission in univariate model and multivariate model [OR: 2.384 insert ignore into journalissuearticles values(95% CI: 1.084-5.246);, p=0.031] vs. [OR: 2.738 insert ignore into journalissuearticles values(95% CI: 1.130-6.635);, p=0.026] and [OR: 5.058 insert ignore into journalissuearticles values(95% CI: 1.968-12.998);, p=0.001] vs. [OR: 4.218 insert ignore into journalissuearticles values(95% CI: 1.521-11.697);, p=0.006]. Anemia was also a risk factor for MV [OR: 2.582 insert ignore into journalissuearticles values(95% CI: 1.075-6.197);, p=0.034]. Conclusion: Requirement for therapy in ICU and MV were high among anemic COVID-19 patients. Anemia is also associated with prolonged length of stay in hospital and ICU.
Keywords : Coronavirus disease 2019 COVID 19, Anemia, Intensive care unit