Clinicopathological and prognostic outcomes of endometriosis-associated ovarian cancer

Authors : Esra Keles, Sahra Sultan Kara, Sadun Sucu

Pages : 102-106

Doi:10.61845/agrimedical.1674787

View : 161 | Download : 297

Publication Date : 2025-10-29

Article Type : Research Paper

Abstract :Aim: The aim of this study is to investigate the clinicopathological characteristics and prognostic value of endometriosis in patients with ovarian cancer. Materials and Methods: A retrospective analysis was performed on 273 patients with ovarian carcinoma between January 2013 and December 2023. Patients were stratified into endometriosis-associated ovarian carcinoma (EAOC) and non-endometriosis-associated ovarian carcinoma (non-EAOC). Clinicopathological variables, including age, menopausal status, tumor size and volume, FIGO stage, histological subtype, serum tumor markers, and survival outcomes, were evaluated. Results: EAOC patients were significantly younger than non-EAOC patients (respectively 51 ± 11.4 years, 59 ± 11.2 years; p = 0.002). EAOC cases were more frequently diagnosed at FIGO stage I than non-EAOC cases (p = 0.001), whereas FIGO stage (III) disease was more prevalent in the non-EAOC group (p = 0.007). No significant differences were observed in CA-125 levels between groups. CA 19-9 levels were elevated in the EAOC group (p = 0.012). Recurrence rates and survival outcomes did not differ significantly between the groups. Conclusion: EAOC cases were diagnosed at a younger age and presented at an earlier FIGO stage and had elevated CA 19-9 levels. However, survival outcomes did not significantly differ between EAOC and non-EAOC groups.
Keywords : Endometriozis, Over neoplazileri, Endometriozisle ilişkili over kanseri, Sağkalım sonucu

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