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  • Volume:8 Issue:4
  • ARTER TAMİRİNDE N-BUTİL-2-SİYANOAKRİLAT (HİSTOAKRİL) KULLANIMI The Using of N-butyl-2-cyanoacrylate ...

ARTER TAMİRİNDE N-BUTİL-2-SİYANOAKRİLAT (HİSTOAKRİL) KULLANIMI The Using of N-butyl-2-cyanoacrylate (Histoacryl) at Artery Mending

Authors : Volkan GÜNEYLİ, Hayati ÖZTÜRK, Seyran KILINÇ, Özhan PAZARCI, Zekeriya ÖZTEMUR, Seyfi Gündüz TEZEREN, Okay BULUT
Pages : 41-50
View : 19 | Download : 22
Publication Date : 2018-12-15
Article Type : Research Paper
Abstract :ÖZET Amaç: Siyanoakrilat birçok cerrahi alanda başarıyla kullanılmakta olup, son yıllarda mikrovasküler anastomoz amacıyla kullanılmaya başlanmıştır. Çalışmamızın amacı geleneksel sütür tekniği ile kendi geliştirdiğimiz siyanoakrilat ile güçlendirilmiş sütür tekniğini karşılaştırmaktır. Gereç ve Yöntemler: Çalışmaya toplam 16 Yeni Zelanda türü tavşan alındı. 8 Tavşan kontrol grubuna, 8 tavşan ise çalışma grubuna dâhil edildi. Sol femoral arterleri hazırlanarak, tam kat kesildi. Kontrol grubunda 90° acı ile dört sutur konularak geleneksel anastomoz uygulandı. Deney grubunda ise ön yüze tek sütür konulup, arka yüzde proksimal parça distalin içine geçirilip, siyanoakrilat damlatılarak anastomoz uygulandı. Klinik değerlendirme ve istatistik analiz yapılarak, operasyon süresi, kanama süresi ve geciş incelendi. Sonuçlar: Anastomoz iyileşmesi, 21. günde tavşanların sakrifiye edilerek alınan biyopsilerin ışık mikroskopisi altında histolojik olarak incelenmesi ile değerlendirildi. İki grup arasında lümen çapları açısından anlamlı fark vardı. Deney grubunda operasyon ve kanama süreleri anlamlı olarak kısa bulundu. Daha fazla endotel kaybı ve inflamasyon görülmesine rağmen akım engellemiyordu. Çıkarım: Uyguladığımız yöntem basit, az sütürle, kısa zamanda gerçekleştirilen, geçiş oranını azaltmayan, bir teknik olarak değerlendirilmiştir. Anahtar Sözcu¨kler: Siyanoakrilat; Mikrovasküler anastomoz; Arter tamiri ABSTRACT Objective: Cyanoacrylate has been successfully used in many surgical fields and it has been also used for microvascular anastomosis in recent years. The purpose of this study is to compare the traditional suture technique with the enhanced cyanoacrylate suture technique that we have developed. Material and Methods: 16 New Zeland rabbits has researched included in this study. Control group includes 8 rabbits and study group includes 8 rabbits. Left femoral arteries were prepared and cut into full layers. Traditional anastomosis was performed by placing four sutures with 90 ° angle in the control group. But the testing group, the anastomosis is applied by putting one suture to the front part, by putting a proximal item in distal at back part and by putting cyanoacrylate in it. Clinical evaluation and statistical analysis were researched, the operation and duration of bleeding with vessel passage were investigated. Results: On day 21, anastomosis healing was histologically examined under light microscopy of the sacrificed rabbits and the results were evaluated. There was a significant difference between the two groups in terms of luminal diameters. Operation and bleeding time is found short at testing group. although there was more endothelial loss and inflammation in the experimental group, blood flow was not prevented. Conclusion: it can be evaluated easy methods what we used, it can be evaluated as a technique that is performed in a short time and does not decrease the blood transit ratio. We think that, there is need to new studies and pratic applications about these subjects. Keywords: Cyanoacrylate; Microvascular anastomosis; Artery mending.
Keywords : ARTER TAMİRİNDE N BUTİL 2 SİYANOAKRİLAT HİSTOAKRİL KULLANIMI The Using of N butyl 2 cyanoacrylate Histoacryl at Artery Mending

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