Identification of Prognostic Markers in Patients with Acute Decompensated Heart Failure

Authors : Adem Köksal, İbrahim Çaltekin, Mehmet Seyfettin Sarıbaş, Mesut Tomakin, Ali Aygun

Pages : 162-168

Doi:10.16919/bozoktip.1632218

View : 43 | Download : 28

Publication Date : 2025-06-15

Article Type : Research Paper

Abstract :Purpose: This study aims to evaluate the effectiveness of prognostic markers in predicting 90-day mortality in patients admitted to the hospital with a diagnosis of acute decompensated heart failure (ADHF). Materials and Methods: This retrospective study analyzed data from 559 ADHF patients admitted between 01.05.2023 and 01.09.2024. Age, sex, laboratory parameters, and 90-day mortality data were collected, and independent variables affecting mortality were evaluated via logistic regression and receiver operating characteristic (ROC) analysis. Results: Age, blood urea nitrogen, albumin, and lactate levels were identified as independent predictors of 90-day mortality. The blood urea nitrogen level demonstrated the highest area under the curve (AUC = 0.673) for a cutoff value of 30.9 mg/dL. A significant increase in mortality risk was observed for patients with lactate levels >1.45 mmol/L. Conclusion: Age, blood urea nitrogen, albumin, and lactate levels are strong prognostic markers for 90-day mortality in patients with ADHF. These findings may contribute to early risk stratification and the development of personalized treatment strategies.
Keywords : Albümin, BUN, Kalp yetersizliği, Laktat, Mortalite, Yaş

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