Antimicrobial activities of different extracts from Centaurea iberica

Authors : Derya Doğanay, Esra Mertoğlu, Bahar Gürdal, Gizem Gülsoy Toplan

Pages : 186-195

Doi:10.53445/batd.1840067

View : 94 | Download : 97

Publication Date : 2025-12-30

Article Type : Research Paper

Abstract :Across different regions of the world, plants have long been valued for their wide range of functional properties. Aromatic plants, in particular, are cultivated to obtain natural compounds used in cosmetic scenting, food enhancement, and preservation. Within this category, species belonging to the Asteraceae family have gained increasing attention in recent years due to their expanding relevance in numerous applied disciplines. The objective of this study was to evaluate the antibacterial and antifungal potential of different solvent extracts (n-hexane, ethyl acetate, and methanol) and an infusion of Centaurea iberica L. against five bacterial (Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, Staphylococcus epidermidis ATCC 12228, Acinetobacter baumannii ATCC 19606, Pseudomonas aeruginosa ATCC 27853) and two yeast (Candida albicans ATCC 10231 and Candida parapsilosis ATCC 22019) strains using the microdilution method. The minimum inhibitory concentration (MIC) values for all tested microorganisms ranged between 78.125 and 5000 µg/mL. According to the results, all studied extracts exhibited stronger antifungal activity than antibacterial activity. Among them, the ethyl acetate extract demonstrated the most potent antifungal effect with MIC values between 78.125 and 156.25 µg/mL, whereas the infusion extract showed the weakest overall activity. In conclusion, further phytochemical investigations are required to identify the secondary metabolites responsible for these activities, which may contribute to the development of novel antifungal agents.
Keywords : Antibakteriyel, antifungal, Centaurea, Asteraceae

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