Hepatitis B antibody Response in Patients with Celiac and Inflammatory Bowel Diseases

Authors : Didem GÜLCÜ TAŞKIN

Pages : 79-83

Doi:10.26650/jchild.2023.1178024

View : 17 | Download : 5

Publication Date : 2023-03-27

Article Type : Research Paper

Abstract :Objective: In some patient groups, special vaccination protocols need to be followed for vaccine preventable diseases like Hepatitis B insert ignore into journalissuearticles values(HB);. We aimed to evaluate the antibody response against the HB vaccine in Inflammatory Bowel Disease insert ignore into journalissuearticles values(IBD); and Celiac Disease insert ignore into journalissuearticles values(CD); patients, emphasizing the efficiency of the routine vaccine protocol for these patient groups. Material and Methods: We included 219 patients insert ignore into journalissuearticles values(CD and IBD); and 125 in the healthy control group insert ignore into journalissuearticles values(HCG);. The patients who had received only 3 doses of HB vaccine were included. The design of the study is retrospective in manner. Results: The patients age with positive antibody insert ignore into journalissuearticles values(anti-HBs titers); were lower than in patients with negative anti-HBs titers. In patients having positive anti-HBs titers, both the serum glutamic-oxaloacetic transaminase insert ignore into journalissuearticles values(SGOT); and serum glutamic-pyruvic transaminase insert ignore into journalissuearticles values(SGPT); values were found to be significantly higher. Result: Following periodic control measures and administering an additional dose of the HB vaccine is required because the antibody protection decreases as the illness continues to progress with the increasing age of the patients.
Keywords : Çölyak Hastalığı ÇH, Hepatit B virüs aşısı, Anti HBs antikor titresi, İnflammatuvar bağırsak hastalığı İBH, çocuk

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