Comparison of De Ritis Rate for Del Nido Versus Blood Cardioplegia in Patients Who Underwent Coronary Artery Bypass Graft Under Cardiopulmonary Bypass

Authors : Bişar Amaç, Murat Ziya Bağış, Mahmut Padak

Pages : 144-148

Doi:10.36516/jocass.1513739

View : 46 | Download : 98

Publication Date : 2024-09-30

Article Type : Research Paper

Abstract :Aim: Within the scope of this research, we aimed to compare the liver function tests, liver enzymes and De Ritis ratio (AST/ALT) of patients given Del Nido cardioplegia and blood cardioplegia in coronary heart surgery. Methods: This retrospective study included a total of 80 patients who underwent CPB-guided coronary heart surgery (CABG) with 40 Del Nido cardioplegia solutions and 40 blood cardioplegia solutions. CPB-guided coronary heart surgery patients given Del Nido cardioplegia solution were determined as the first group (Group 1), and patients given blood cardioplegia were determined as the second group (Group 2). Results: Preoperative and postoperative aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, direct bilirubin, and gamma-glutamyl transferase (GGT) levels of the groups were similar (p<0.005). AST, ALT, total bilirubin, direct bilirubin, and GGT levels were similar in CPB output (p<0.005). The De Ritis ratio of the groups was similar on the preoperative and postoperative 1st day (p=0.072; p=0.687, respectively), and the rate of ritis at CPB output was higher in group 2 (p=0.003). The requirement for defibrillation was higher in group 1 (p=0.044). Conclusion: The Del Nido cardioplegia solution may be superior to blood cardioplegia in CABG cases accompanied by CPB regarding the De Ritis ratio.
Keywords : Cardiopulmonary bypass, coronary artery bypass graft, del nido cardioplegia, blood cardioplegia, de ritis rate

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