Evaluating the Therapeutic Impact of Autologous Platelet-Rich Plasma (PRP) on Long Bone Fracture Healing in Cats

Authors : Nail Deniz Yaşrın, İrem Ergin

Pages : 36-44

Doi:10.32707/ercivet.1610440

View : 77 | Download : 61

Publication Date : 2025-04-18

Article Type : Research Paper

Abstract :This study evaluated the clinical and radiographic effects of platelet-rich plasma (PRP) on the healing of long bone fractures in cats. It featured a control group (n= 11) and a PRP group (n= 11). In the control group, only osteosynthesis was performed, whereas the PRP group received a combination of PRP and a gelatin sponge applied to the osteosynthesis site. Clinical and radiographic evaluations were conducted on days 0 (preoperative), 15 and 30 (postoperative). Clinical evaluation included lameness scoring, while radiographic assessment focused on fracture healing according to the Hammer scale, fracture reduction, intramedullary pin positioning, and callus formation. A significant reduction in lameness scores was observed on the 15th and 30th days in both groups. Although no statistically significant differences were detected between the groups on days 15, and 30, the PRP Group demonstrated lower scores. Based on the evaluations performed using the Hammer scale, no statistically significant differences were observed between the groups in callus formation and fracture line scores at the postoperative time points of days 15 and 30. However, upon examining the union score, the difference observed between the two time periods was found to be statistically significant, with a more pronounced effect in the PRP group on day 15. In conclusion, no complications were observed during the study. While PRP did not significantly alter the overall clinical healing process of long bone diaphyseal fractures in cats, it was found to accelerate early healing and reduce lameness.
Keywords : Büyüme faktörü, felin, intramedullar pin, kallus, trombosit