Investigation of Cytomegalovirus Serology in Adult Individuals in Erzurum Region.

Authors : Mahmut Ucar, Ahmet Yılmaz, Gürsel Bedir

Pages : 104-109

Doi:10.54005/geneltip.1536319

View : 7 | Download : 20

Publication Date : 2025-02-28

Article Type : Research Paper

Abstract :Aims: Cytomegalovirus, a double-stranded DNA virus in the family Herpesviridae, like other known herpes viruses, remains latent throughout a person\\\'s life following the initial infection in CMV and causes recurrent infections. The aim of the study was to reveal the current status of CMV seroprevalence in adults in Erzurum and to investigate the trends in CMV infection by comparing the obtained seroprevalence data with the previously reported data. Materials and Methods: In our study, the results of people whose anti-CMV IgG and anti-CMV IgM serology were investigated by family physicians in Erzurum between 2020-2023 were retrospectively analyzed. Blood samples of individuals were studied in Erzurum Public Health Serology Laboratory using the ELISA method using the Architect kit. In order to make comparisons between individuals, the working group; It was divided into 6 different age groups: 18-24, 25-29, 30,34, 35-39, 40-49 and ≥50. Results: The population of our study consisted of 9,252 people between the ages of 18 and 103 who were investigated for anti-CMV IgG serology, and 13,276 people between the ages of 18 and 97 for anti-CMV IgG. Anti-CMV IgG seropositivity was 98.5% and anti-CMV IgM seropositivity was 2.1% in our study group. Anti-CMV IgG and IgM positivity were 98.7% and 2.1%, respectively, in women; 97.7% and 2.2% in men. Conclusions: In our study, anti-CMV IgG seropositivity was found to be 98.7%, anti-CMV IgM seropositivity was found to be 2.1%, and CMV IgG seropositivity rates were found to be higher in our province compared to similar studies conducted in our country. The CMV IgM seropositivity rate is consistent with the data from Turkey.
Keywords : Sitomegalovirüs, anti-CMV IgG, anti-CMV IgM, prevalans, Erzurum