Pleural Fluid Gas Analysis in Diagnosing and Differentiating Pulmonary Diseases

Home Page
About
Submit A Journal
Submit A Conference
Submit Paper/Book
- Submit a Preprint
- Submit a Book
Contact

Harran Üniversitesi Tıp Fakültesi Dergisi
Cilt: 22 Sayı: 2
Pleural Fluid Gas Analysis in Diagnosing and Differentiating Pulmonary Diseases

Pleural Fluid Gas Analysis in Diagnosing and Differentiating Pulmonary Diseases

Authors : İdris Kırhan, Aliye Gamze Çalış, Fatih Üzer, Bedia Karaçadır, Hamdiye Turan

Pages : 351-356

Doi:10.35440/hutfd.1659543

View : 32 | Download : 46

Publication Date : 2025-06-27

Article Type : Research Paper

Abstract :Background: This study aimed to evaluate pleural fluid gas parameters in patients with different underl-ying pulmonary diseases to assess their diagnostic implications. Materials and Methods: This study conducted at Akdeniz University Pulmonology Department and Har-ran University Pulmonology Department. The retrospective study included 118 patients with pleural effusion confirmed via imaging between January 2018 and December 2024. Pleural fluid samples collec-ted by thoracentesis underwent gas analysis (pO₂, pCO₂, pH, HCO₃) and standard biochemical and cytolo-gical evaluations. Comparative analysis of gas characteristics was performed across diagnostic categories with a significance threshold of p < 0.05. Results: In this study, 87 of 118 patients underwent arterial blood gas analysis, with a mean age of 66.4±14.2 years and 72.4% being male. Acidic, normal, and alkaline pleural fluid pH values were obser-ved in 25.3%, 26.4%, and 48.3% of patients, respectively. Most effusions were exudative (83.9%), and unilateral (81.6%), with malignancy (29.9%), pneumonia (35.6%), and heart failure (16.1%) being the leading causes. Among pneumonia cases, 45.1% had complicated effusions or empyema. Transudative effusions were associated with older age, higher pH, and lower LDH, pCO₂, and protein levels (p<0.05). Compared to other causes, pneumonia-related effusions were more likely to be exudative, occur in males, and have higher protein levels. Malignant effusions showed significantly higher HCO₃ and protein levels (p<0.05). Conclusions: Pleural fluid gas analysis may offer valuable diagnostic insights, particularly in differentia-ting infectious from non-infectious effusions.
Keywords : plevral efüzyon, pnömoni, pulmoner hastalıklar

ORIGINAL ARTICLE URL

* There may have been changes in the journal, article,conference, book, preprint etc. informations. Therefore, it would be appropriate to follow the information on the official page of the source. The information here is shared for informational purposes. IAD is not responsible for incorrect or missing information.