Variability of serum anti-Mullerian hormone level and antral follicle count in an unstimulated menstrual cycle

Authors : Merve DİZDAR, İbrahim KALE, İlgi ESEN, Rahime BAYIK

Pages : 1735-1741

Doi:10.38136/jgon.1162167

View : 29 | Download : 86

Publication Date : 2023-07-03

Article Type : Research Paper

Abstract :Aim: To evaluate the variability of anti-Mullerian hormone insert ignore into journalissuearticles values(AMH); and antral follicle count insert ignore into journalissuearticles values(AFC); in an unstimulated menstrual cycle. Materials and Method: The study was designed on 50 women who had regular menstrual cycles and did not have any systemic disease or previous ovarian surgery. Serum AMH levels and antral follicle counts of all participants were evaluated three times in the same menstrual cycle in the early and late follicular phase and luteal phase. To evaluate the intracyclic AMH fluctuation according to age, participants were divided into two groups; younger insert ignore into journalissuearticles values(<35 years); and older insert ignore into journalissuearticles values(35 years old);. Results: The mean age of the participants was 30.8, the mean BMI was 23.4 kg/m2, and the mean menstrual cycle duration was 28.5 days. Mean AMH values evaluated at three different times in the menstrual cycle, early follicular, late follicular, and luteal phase, were 2.66 ng/dl and mean AFC 17.4. The highest mean AMH level and AFC were detected in the late follicular phase and this was statistically significant for AMH level but not for AFC insert ignore into journalissuearticles values(p= 0.044, p=0.307, respectively);. The intracyclic fluctuation of AMH was greater in the younger patient group. The coefficient of variation was 0.241 in the younger patient group, and 0.132 in the older patient group. insert ignore into journalissuearticles values(p=0.011); Conclusion: Serum AMH levels fluctuate throughout the menstrual cycle and the highest serum AMH level was detected in the late follicular phase. AFC remained stable throughout the cycle.
Keywords : Anti Mullerian hormon, menstruel siklus, over rezervi, antral follikül sayısı, intra siklik variabilite