Platelet Transfusion: Is it a Risk Factor for the Development of Premature Retinopathy?

Authors : Duygu Tunçel, Sevdet Balık, Leyla Şero, Dilbade Yıldız Ekinci, Nilufer Okur

Pages : 51-55

Doi:10.38136/jgon.1481253

View : 42 | Download : 41

Publication Date : 2025-03-22

Article Type : Research Paper

Abstract :Aim: To determine the potential relationship between platelet transfusions and the development of premature retinopathy. Materials and Method: This is a retrospective, cross-sectional, case-control study. Premature infants with gestational age 2) and those who did not. Demographic data, short and medium-term morbidities, presence of transfusion, and transfusion numbers were recorded from the hospital data system and patient files. Conditional logistic regression analysis was performed to adjust for matching. Results: A total of 130 premature infants were included in the study between January 2017 and January 2021. ROP was detected in 80 (61.5%) patients. In the groups with and without ROP, birth weights were 1201±256 g and 1035±341 g (p=0.03), gestational ages were 28.6±2 weeks and 27.5±2 weeks (p=0.06), respectively. Twenty-one patients received platelet transfusions. The number of platelet transfusions was higher in the ROP group (p<0.01). There was a significant correlation between the number of platelet transfusions and the need for ROP treatment (-0.21, p=0.016). Conclusions:A significant relationship was found between the number of platelet transfusions and the development of retinopathy requiring treatment. More prospective randomized controlled studies are needed to establish a link between severe retinopathy development and platelet transfusions.
Keywords : Trombosit transfüzyonu, prematürite, retinopati