The Utility of Albumin-Bilirubin Score as a Prognostic Marker in Preeclampsia

Authors : Osman Onur Özkavak, Dilek Sahin

Pages : 19-25

Doi:10.38136/jgon.1629392

View : 43 | Download : 69

Publication Date : 2025-03-22

Article Type : Research Paper

Abstract :Aims: To evaluate the utility of the albumin bilirubin (ALBI) score as a liver function test and prognostic marker in patients with preeclampsia. Materials and Methods: A total of 374 patients were enrolled in the study (148 preeclampsia without severe features, 112 preeclampsia with severe features, 114 controls). The study compared clinical and demographic features, laboratory findings and ALBI scores between the three groups. Also, receiver operating curve (ROC) analysis was used for the estimation of the predictive value of the ALBI score for the severity of preeclampsia and maternal/neonatal poor prognosis. Results: The median ALBI score of the severe preeclampsia group was significantly higher than mild preeclampsia and control groups (p<0.001 and p<0.001 respectively). Also mild preeclampsia group had a higher ALBI score than the control group (p=0.039). The ROC curve analysis for the predictive value of ALBI score for maternal poor prognosis in preeclamptic patients showed an area under the curve (AUC) of 0.774 (95% CI 0.671 – 0.776, p<0.001). In the ROC curve analysis performed to investigate the value of ALBI score in neonatal poor prognosis prediction, the AUC was calculated as 0.55 (95% CI 0.48 – 0.62, p=0.164). For the prediction of preeclampsia with severe features in all preeclampsia cases, the AUC was 0.751 (95% CI 0.691-0.812, p<0.001) Conclusion: The ALBI score could be a useful, cost-effective and practical liver function test and prognostic marker for patients with preeclampsia. However, the predictive performance for neonatal poor prognosis was not sufficient.
Keywords : Preeklampsi, Albumin-bilirubin skoru, ALBI skoru