The inflammatory prognostic index predicts new-onset atrial fibrillation in patients after primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction

Authors : Yavuz Karabağ, Talha Karahan, Soner Kina, Yüksel Erata, Öztürk Demir

Pages : 112-118

View : 36 | Download : 13

Publication Date : 2025-04-30

Article Type : Research Paper

Abstract :Introduction&Objective: New-onset atrial fibrillation (NOAF) is an independent predictor of mortality and a strong indicator of poor prognosis following ST-segment elevation myocardial infarction (STEMI). The Inflammatory Prognostic Index (IPI) is clinically significant in predicting patient outcomes and serves as a novel inflammatory prognostic marker based on C-reactive protein (CRP), the neutrophil-to-lymphocyte ratio (NLR), and serum albumin levels. This study aimed to investigate the relationship between the IPI and NOAF in patients with STEMI who underwent primary percutaneous coronary intervention (pPCI). Material&Methods: The population for this retrospective study consisted of 1,132 consecutive patients diagnosed with STEMI who underwent pPCI. Out of these, 946 patients were included in the study sample and were divided into two groups based on whether they developed NOAF or not. Results: The study’s primary outcome, that is, IPI was significantly higher in patients with NOAF than in those with No-AF (42.15 (17.6-81.7) vs. 12.77 (5.72-27.01), p 17.5 predicted NOAF with 76% sensitivity and 62.7% specificity (AUC: 0.740 [95% CI: 0.711–0.768, p<0.0001] (P<0.0001). Conclusion: This study finds that the IPI independently predicts NOAF in STEMI patients treated with pPCI.
Keywords : Inflammatory prognostic index, ST-segment elevation myocardial infarction, Atrial fibrillation.