ANXIETY AND DEPRESSION IN TYPE 2 DIABETES MELLITUS: A STUDY INCLUDING NERVE CONDUCTION STUDY AND NEUROPATHIC PAIN

Authors : Şencan BUTURAK, Halit FİDANCI, Mehmet YILDIZ, Zülfikar ARLIER

Pages : 76-84

Doi:10.24938/kutfd.1113995

View : 21 | Download : 10

Publication Date : 2023-04-30

Article Type : Research Paper

Abstract :Objective: It is known that neuropathy, neuropathic pain and psychiatric disorders are associated with diabetes mellitus insert ignore into journalissuearticles values(DM);. It was aimed to find out whether there is a relationship between nerve conduction study findings, neuropathic pain, depression and anxiety. Material and Methods: Type 2 DM patients that applied to our clinical neurophysiology laboratory between September 2021 and January 2022 were included in this study. Median, ulnar, sural, peroneal and posterior tibial nerve conduction studies were performed on the patients. Douleur Neuropathique 4 Questions insert ignore into journalissuearticles values(DN4); was applied to the patients to evaluate neuropathic pain. Hospital Anxiety and Depression Scale insert ignore into journalissuearticles values(HADS); was applied to the patients. Anxiety insert ignore into journalissuearticles values(HADS-A); and depression insert ignore into journalissuearticles values(HADS-S); scores, which are the two subsections of HADS, were included in the analysis. Results: Forty DM patients insert ignore into journalissuearticles values(27 males, 13 females); were included in the study. The mean age of the patients was 57.9±12.7 insert ignore into journalissuearticles values(min-max 23-83); years. The number of patients with neuropathic pain, polyneuropathy according to neurophysiological findings, abnormal HADS-A and HADS-D scores were 32 insert ignore into journalissuearticles values(80%);, 23 insert ignore into journalissuearticles values(58%);, 17 insert ignore into journalissuearticles values(43%);, and 24 insert ignore into journalissuearticles values(60%);, respectively. Neuropathic pain was present in 22 insert ignore into journalissuearticles values(96%); and 10 insert ignore into journalissuearticles values(59%); of the patients with and without polyneuropathy, respectively. Neuropathic pain was found in 22 insert ignore into journalissuearticles values(92%); patients with depression and 16 insert ignore into journalissuearticles values(63%); patients without depression insert ignore into journalissuearticles values(p=0.046);. Among patients with neuropathic pain, compound nerve action potential amplitudes of median, ulnar and sural nerves were lower than those without neuropathic pain insert ignore into journalissuearticles values(p=0.011, p=0.027, p<0.001);. Conclusion: In this study, it was revealed that neuropathic pain, depression and anxiety can be seen in Type 2 DM patients. In addition, this study showed a relationship between sensory nerve conduction studies and neuropathic pain. It was also concluded that neuropathic pain was more common in DM patients with depression than in patients without depression.
Keywords : Anksiyete, depresyon, diabetes mellitus, sinir iletim çalışması, nöropatik ağrı