COMPARISON OF 18F-FDG PET/CT DATA WİTH TYPE 2 DIABETES AND OBESITY IN BREAST CANCER

Authors : Özge Ulaş Babacan, Zekiye Hasbek
Pages : 306-311
Doi:10.24938/kutfd.1696624
View : 48 | Download : 87
Publication Date : 2025-12-25
Article Type : Research Paper
Abstract :Objective: The aim of the present study was to evaluate the association of obesity and diabetes with 18F-FDG PET/CT SUVmax values and metastasis in breast cancer patients. Material and Methods: The study included 126 breast cancer patients who underwent 18F-FDG PET/CT for staging between 2023 and 2024. Results: There was no significant correlation between the presence of obesity and breast tumour SUVmax value (p=0.427). There was no significant relationship between body mass index and metastatic lymph node SUVmax and distant metastasis SUVmax (p=0.06, p=0.457). There was no significant association between the presence or absence of diabetes and distant metastasis SUVmax or lymph node metastasis SUVmax on 18F-FDG PET/CT (p=0.723, p=0.581). In our study, there was no significant difference in the 18F-FDG PET/CT findings of breast cancer patients with diabetes at the time of diagnosis compared to women without diabetes. In addition, although not statistically significant, we found that the median SUVmax values for lymph node and distant metastases were significantly higher in obese and morbidly obese patients compared to other patients. Therefore, we think that breast cancer patients should be followed up more closely in the follow-up of obese and diabetic patients, taking these conditions into consideration and patients should be advised to lose weight. Conclusion: In conclusion, although we did not find a significant association between body mass indeks and diabetes and breast cancer in our study, we think that this may be due to the small number of patients. We also found that the risk of axillary lymph node metastasis increased as breast tumor SUVmax increased and the cut-off value for breast tumor SUVmax was 5.15. We think that the presence of lymph node metastasis on PET/CT should be reported carefully, taking into account the SUVmax value.
Keywords : Meme kanseri, beden kitle indeksi, diyabet

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