Determination of Antimicrobial Activities of Methanolic Extracts of Some Medicinally Important Plants Found Around Çorum Province

Authors : Demet Tatar, Aysel Veyisoğlu, Hünkar Avni Duyar, Rukiye Yılmaz

Pages : 375-381

Doi:10.29278/azd.1788621

View : 47 | Download : 34

Publication Date : 2025-12-29

Article Type : Research Paper

Abstract :Objective: This study aimed to investigate the antimicrobial activities of methanolic extracts obtained from ten medicinal plants traditionally used in Çorum province, Türkiye. Materials and Methods: Plant samples were collected in the spring season, dried, and extracted using 70% methanol. The antimicrobial activities of the extracts were tested by the disk diffusion method against three Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis), three Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa), and two fungi (Candida albicans, Aspergillus niger). Ampicillin, Polymyxin B, and Nystatin were used as positive controls. Results: The results showed that nine plant extracts exhibited inhibitory effects against K. pneumoniae, while all extracts inhibited B. subtilis. Seven extracts were active against E. faecalis, whereas acorn and oleaster extracts displayed limited antifungal activity against A. niger. No inhibitory activity was observed against S. aureus, E. coli, P. aeruginosa, and C. albicans. Conclusion: The findings suggest that several plant extracts commonly used in Çorum possess notable antimicrobial potential. Extracts particularly effective against B. subtilis and E. faecalis may serve as promising sources for the development of novel natural antimicrobial agents. Further studies should focus on isolating and characterizing the bioactive compounds responsible for these effects.
Keywords : Tıbbi bitkiler, metanol ekstraktı, antimikrobiyal aktivite, Çorum

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