RETROSPECTIVE INVESTIGATION OF ARTHRITIS CASES DETECTED IN CHILDHOOD

Authors : Hatice Büyükoflaz, Muhammed Yaşar Kılınç

Pages : 94-99

Doi:10.18229/kocatepetip.1291101

View : 47 | Download : 39

Publication Date : 2025-04-28

Article Type : Research Paper

Abstract :OBJECTIVE: In this retrospective study, we aimed to evaluate the etiology of arthritis by examining the anamnesis, physical examination and laboratory tests of the patients between 01.01.2012 and 31.12.2014 in Karaman Training and Research Hospital Pediatrics Department. MATERIAL AND METHODS: The data of 101 patients were retrospectively analyzed. We recorded the results of laboratory investigations, including complete blood count (CBC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), blood culture, antinuclear antibody (ANA), antistreptolysin-O (ASO), rheumatoid factor (RF), Familial Mediterranean Fever (FMF) gene mutation, and serological tests including hepatitis viruses, human immunodeficiency virus, Salmonella, Mycoplasma pneumoniae (M. pneumonia), Chickenpox, Epstein-Barr virus, parvovirus, Rubella, Yersinia,Campylobacter, Brucella, and microbiological tests such as culture were analyzed. RESULTS: The age at initial presentation ranged from 1 to 17 years (mean: 9.74±3.9). In our study, the M/F ratio of 101 patients was 1.4. Diagnostic analysis revealed that 32% of the patients had transient arthritis, 15% had juvenile idiopathic arthritis (JIA), 12% had acute rheumatic fever (ARF), 10% had IgA vasculitis, 8% had reactive arthritis (RA), 6% had Brucella arthritis, 6% had poststreptococcal reactive arthritis (PSRA), 3% had Familial Mediterranean Fever (FMF), 3% had urticarial vasculitis, 2% had arthritis associated with Kawasaki disease, 2% had septic arthritis, and 1% had viral arthritis. In our study, 45.5% of the patients had a recent upper respiratory tract infection history. Leukocytosis was present in 42.4% of patients, elevated CRP in 45.5%, and elevated ESR in 54.8%. Joint involvement was acute (<2 weeks) in 76.3% of patients, subacute (2-6 weeks) in 4.9%, and chronic (>6 weeks) in 18.8%. The most common complaints were knee pain (57.3%) and ankle pain (31.6%). Additional symptoms included fever (36.6%), rash (15.8%), and muscle pain (6.9%). In patients with ARF, RA, and Juvenile Idiopathic Arthritis (JIA), the knee was the most commonly affected joint, while the ankle was most frequently involved in patients with IgA vasculitis and FMF. CONCLUSIONS: In patients diagnosed with arthritis, the duration of symptoms, migratory or persistent nature of arthritis, the number of affected joints, associated symptoms, family history, physical examination findings, elevated acute-phase reactants, and additional laboratory tests are key factors may be helpful in the differential diagnosis. Although history and physical examination findings are very important in the diagnosis, laboratory findings are also valuable.
Keywords : Artrit, Çocuk, Etyoloji, Klinik özellikler

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