Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Authors : Şükrü DEĞİRMENÇAY, Muhammed Sertaç EROĞLU, Emre EREN

Pages : 77-85

Doi:10.30607/kvj.1205080

View : 17 | Download : 11

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :The most common enteropathogens causing diarrhea in neonatal calves are Escherichia coli insert ignore into journalissuearticles values(E. coli); and rotavirus. Procalcitonin insert ignore into journalissuearticles values(PCT); is a parameter that has recently become widely used to determine whether infectious diseases are caused by bacteria. Iron is an essential nutrient for almost all bacterial species, and serum iron levels are used as an inflammatory biomarker. Therefore, in this study, we aimed to investigate the differential diagnosis value of serum iron and procalcitonin levels in E. coli and rotavirus diarrhea. The material of the study consisted of 30 calves 1-15 days old. Three groups were formed as: E. coli insert ignore into journalissuearticles values(n=10);, rotavirus insert ignore into journalissuearticles values(n=10); and control insert ignore into journalissuearticles values(n=10);. Calves in the E. coli group had the highest PCT insert ignore into journalissuearticles values(P=0.005); and CRP insert ignore into journalissuearticles values(P=0.003); levels, as well as the lowest Fe insert ignore into journalissuearticles values(P=0.000); levels. As a result, it was determined that serum Fe levels could be used as an inflammatory marker and PCT levels higher than 50 pg/mL could be used in the differential diagnosis of E. coli diarrhea in calves with 100% sensitivity and 100% specificity.
Keywords : Diarrhea, Escherichia coli, Iron levels, Procalcitonin, Rotavirus