The Relationship between Smoking Status, Carbon Monoxide Levels and Quality of Life, Disease Characteristics in Inflammatory Bowel Diseases

Authors : Yıldız KIRAÇ, Bektaş YALÇIN, Müge USTAOĞLU

Pages : 69-77

Doi:10.18521/ktd.1186958

View : 19 | Download : 11

Publication Date : 2023-03-15

Article Type : Research Paper

Abstract :Objective: The aim of the study was to analyze the relationship between smoking status and exhaled carbon monoxide insert ignore into journalissuearticles values(E-CO); levels, quality of life, and disease characteristics in patients with inflammatory bowel disease. Methods: The demographic and disease characteristics and smoking status of 121 patients with inflammatory bowel disease who presented our hospital between 01.12.2020 and 01.03.2021 were investigated. After the first follow-up, the E-CO levels of these participants were measured every four consecutive weeks. The mean of these E-CO readings was accepted as the main E-CO value. After one month after their first application SF-36 Quality of Life Scale was applied. The relationship between these variables was investigated. Results: The mean age of the participants was 42.06±14.9 years, and 36.3% were active smokers. While patients with Crohn’s disease insert ignore into journalissuearticles values(CD); exhibited a higher smoking rate, smokers with ulcerative colitis insert ignore into journalissuearticles values(UC); registered significantly higher mean CO ppm readings insert ignore into journalissuearticles values(p<0.05);. The general health components of smoker UC patients were higher than those of non-smokers insert ignore into journalissuearticles values(p<0.05);. A weak correlation was determined between mean number of cigarettes smoked per day, mean CO ppm, Fagerström Nicotine Dependency Test insert ignore into journalissuearticles values(FNDT);, package year, and the physical and mental components of SF-36 in the UC group insert ignore into journalissuearticles values(p<0.05);. There was a weak negative correlation between mental components and mean E-CO in the CD group insert ignore into journalissuearticles values(p=0.027);. No difference was observed in the non-smoker group between participants exposed to second-hand smoke and those with no such exposure insert ignore into journalissuearticles values(p>0.05);. Conclusion: Our results revealed that smoking has a weak positive effect on the quality of health in patients with UC, but no effect on patients with CD.
Keywords : Crohn hastalığı, inflamatuar barsak hastalığı, karbon monoksit, sigara, ülseratif kolit