Prevalence and Pattern of Antibiotic Susceptibility of Gram-Negative Bacteria Isolated from Pediatric Blood Culture

Authors : Engin Turan, Mehmet Bayraktar, Bashar Ibrahım

Pages : 1-14

Doi:10.24998/maeusabed.1392677

View : 42 | Download : 49

Publication Date : 2024-05-02

Article Type : Research Paper

Abstract :It was aimed to evaluate the antibiotic susceptibilities of Gram-negative bacteria isolated from blood samples taken from pediatric patients. The samples were evaluated with the Bactec 9120 automation system bacteria were identified by the Gram-Negative ID panel using the Vitek 2 Compact (Biomerieux France) device performed with the AST N090 panel, and the results were evaluated according to The Clinical and Laboratory Standards Institute (CLSI) recommendations. Antibiotic resistance results: Ceftriaxone was the most resistant antibiotic (71.4%). Salmonella spp. it was mostly resistant to levofloxacin and ciprofloxacin (100%). While E. coli strains were the most resistant to ticarcillin and piperacillin (71.4%), the most effective antibiotics against this bacterium were imipenem and meropenem (100%). Resistance rates to all tested antibiotics were significantly higher in ESBL-producing Klebsiella spp and E coli strains than in non-ESBL-producing strains (p<0.05). Considering this information, it is vital to evaluate the current resistance profiles in the application of empirical treatment in premature and newborn patients.
Keywords : Çocuk, Kan Kültürü, Gram Negatif, Antibiyotik Direnci, Vitek 2