Investigation of plasma pepsinogen level in calves with abomasal distention

Authors : Nuri MAMAK, Ramazan YILDIZ, Halil İbrahim GÖKÇE, Türker ATCALI

Pages : 155-160

Doi:10.24880/maeuvfd.1110471

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Publication Date : 2022-12-31

Article Type : Research Paper

Abstract :The aims of the present study was to determine whether or not abomasal damages occurs in calves with abdominal distention using by plasma pepsinogen levels and the positivity of the fecal occult blood test insert ignore into journalissuearticles values(FOBT);. In the study, 30 calves with abdominal distention insert ignore into journalissuearticles values(distention group); and 15 clinically healthy calves insert ignore into journalissuearticles values(control group);, aged between 1-90 days, were used. Collected plasma samples of all the calves were used to determine plasma pepsinogen levels, using bovine specific ELISA. Fresh stool samples were also taken from the rectum of all the calves and used to determine occult blood in the samples. In the study, melena and occult blood were detected in 11 and 19 of the stool samples, respectively. The plasma pepsinogen levels of calves with abdominal distention insert ignore into journalissuearticles values(18.06±7.78 ng/ml); were significatly high compared to those of control group insert ignore into journalissuearticles values(6.70±2.08 ng/ml);, insert ignore into journalissuearticles values(p<0.001);. In addition, plasma pepsinogen levels were higher in melena insert ignore into journalissuearticles values(+); animals than both FOBT insert ignore into journalissuearticles values(+); and control animals insert ignore into journalissuearticles values(p<0.001);. It is suggestive that plasma pepsinogen levels can be used to determine abomasal damage in calves with gastrointestinal problems, especially with abdominal distention. It can be also useful biomarker to determine the severity of abomasal bleeding and therefore the severity of abomasal damage in calves.
Keywords : Abomasal distention, abomasum ulceration, pepsinogen, calf