Relationship Between Dipper/Non-Dipper Pattern and Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Geriatric Patients with Hypertension

Authors : Perihan Varım, Ahmet Can Çakmak

Pages : 76-81

Doi:10.26453/otjhs.1619335

View : 36 | Download : 58

Publication Date : 2025-03-17

Article Type : Research Paper

Abstract :Objective: Neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) are inflammatory markers associated with poor prognoses. Non-dipper hypertension (HT) is linked to a higher risk for cardiovascular events. This study aims to investigate the association between NLR and PLR in geriatric patients with dipper and non-dipper HT. Materials and Methods: A total of 124 geriatric patients with HT were included in the study. Based on ambulatory blood pressure monitoring, patients were categorized into two groups: non-dippers (n=62, Group 1) and dippers (n=62, Group 2). NLR and PLR were calculated by dividing the absolute neutrophil and platelet counts, respectively, by the absolute lymphocyte count. Results: There were no significant differences in sex, age, chronic conditions and smoking between the two groups (p>0.005). The NLR was 1.96±0.66 in group 1 and 1.67±0.68 in group 2 (p:0.005). The PLR was 146±42.2 in group 1 and 115±34.2 in group 2 (p:0.001). The NLR and PLR were significantly higher in non-dippers compared to dippers (p<0.005). Conclusion: Our findings demonstrate that geriatric patients with non-dipper HT have significantly higher NLR and PLR compared to those with dipper HT. This suggests that non-dipper HT is associated with greater inflammation, which may contribute to its higher cardiovascular risk.
Keywords : Dipper, geriatrik hastalar, NLR, non dipper, PLR