Phytochemistry, Ethnomedicinal Uses and Pharmacological Properties of Rhamnus prinoides: A Review

Authors : Gashaw NİGUSSİE, Mekdes ALEMU, Fozia IBRAHİM, Yemane WEREDE, Metasebia TEGEGN, Sebsib NEWAY, Milkyas ENDALE ANNİSA

Pages : 136-151

Doi:10.21448/ijsm.833554

View : 22 | Download : 30

Publication Date : 2021-06-15

Article Type : Review Paper

Abstract :Rhamnus prinoides L’Herit belongs to Rhamnaceae family widely distributed in India, Eastern, Central and Southern Africa. In Ethiopia it is commonly known as Gesho insert ignore into journalissuearticles values(Amharic, Tigrigna and Afan Oromo);, Gishe insert ignore into journalissuearticles values(Guragegna); and Geshu insert ignore into journalissuearticles values(Agewgna);. Decoction of the leaves is recommended as remedy for treatment of variety of diseases such as back pain, malaria, pneumonia, sexually transmitted disease, skin infections, wounds, blood purifiers, water borne diseases and as ethnoveterinary medicine. Various secondary metabolites such as flavonoids, alkaloids, tannins, terpenoids, saponins, steroids and anthraquinones have been reported from the genus of which polyphenols were abundant with tremedousantioxidant, wound healing and antiinflammatory activities. The plant also serve as hopping agent, making traditional alcoholic beverages like tella and tej insert ignore into journalissuearticles values(in Ethiopia);, animal feed, medicine, nectar for bees, soil conservation, ornamental, shade and dyes in textiles. This review presents chemical profile as well as biological activities of the species which confirmed that the plant is a good source natural polyphenols and provided valuable information in support of its use as an alternative medicine for future healthcare practice.
Keywords : Traditional uses, Chemical constituents, Antiinflammatory activity, Antioxidant activity, Rhamnus prinoides